Ramirez, Nattel, Courtemanche Model of Canine Atrial Cardiac Action Potentials, 2000

This model simulates canine atrial action potentials. The models formulation is based on Luo-Rudy II guinea-pig ventricular model with currents modified to mimic the configuration of canine atrial action potential.

Abstract excerpt: "To obtain insights into the ionic mechanisms governing canine atrial AP properties, we incorporated formulations of K(+), Na(+), Ca(2+), and Cl(-) currents, based on measurements in canine atrial myocytes, into a mathematical model of the AP."

• Ramirez RJ, Nattel S, Courtemanche M.
  Mathematical analysis of canine atrial action potentials: rate, regional factors, and electrical remodeling.
  Am J Physiol Heart Circ Physiol. 2000 Oct;279(4):H1767-85.
  PMID: 11009464

• Order this model via a secure site.